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Jun 6, - No. 2: Pain or Discomfort in the Chest, Throat, Jaw, Shoulder, Arm, or Abdomen. Chest pain could be pneumoniaor a heart attack. The discomfort associated with heart diseasecould also be in the upper chest, throat, jaw, left shoulder or arm, or abdomen and might be accompanied by nausea. Sep 22, - But if you have pain or pressure in the center of your chest that spreads up into your throat or jaw, it could be a sign of a heart attack. Call ‎Atrial Fibrillation · ‎A Visual Guide to a Heart Attack · ‎Silent Symptoms.